{"id":40168,"date":"2023-07-15T07:14:00","date_gmt":"2023-07-15T07:14:00","guid":{"rendered":"https:\/\/www.bensnaturalhealth.com\/blog\/?post_type=diabeteshealth&#038;p=40168"},"modified":"2026-05-27T05:42:10","modified_gmt":"2026-05-27T05:42:10","slug":"wegovy-vs-mounjaro","status":"publish","type":"post","link":"https:\/\/www.bensnaturalhealth.com\/blog\/diabetes-health\/wegovy-vs-mounjaro\/","title":{"rendered":"Wegovy vs Mounjaro: Benefits, Results, Side Effects, Cost"},"content":{"rendered":"\n<p>GLP-1 receptor agonist medications have been all over the news lately.&nbsp;<\/p>\n\n\n\n<p>Not only can GLP-1 receptor agonists help lower blood sugar levels in people with type 2 diabetes, but they\u2019re wildly popular for their potential weight loss benefits in people without diabetes, too.<\/p>\n\n\n\n<p>Certain GLP-1 receptor agonists are approved to use for weight loss in people without diabetes, while others are only meant to treat diabetes.&nbsp;<\/p>\n\n\n\n<p>In this article, we\u2019ll compare a GLP-1 receptor agonist used for weight loss (Wegovy) vs a dual GLP-1 receptor agonist and glucose-dependent insulinotropic polypeptide (GIP) for treating diabetes (Mounjaro).&nbsp;<\/p>\n\n\n\n<p>They both can result in weight loss, but which one might be right for you? We have the answers here!<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-about-wegovy-semaglutide\">About Wegovy (Semaglutide)<\/h2>\n\n\n\n<p>Wegovy (semaglutide) is a prescription weight-loss medication. It\u2019s an injectable medication with once-weekly dosing, and it shares the same active ingredient (semaglutide) as Ozempic, a popular medication for type 2 diabetes (though they are <em>not<\/em> the same and are intended for different purposes).<\/p>\n\n\n\n<p>Wegovy was approved by the United States Food and Drug Administration in 2021 for weight management and weight loss.&nbsp;<\/p>\n\n\n\n<p>Wegovy is meant to be used by people 18 years and older with a body mass index (BMI) of 27 or higher, which indicates being \u201coverweight.\u201d<\/p>\n\n\n\n<p>The dosage of Wegovy starts at 0.25 milligrams per week and can be increased to a maximum of 2.4 milligrams per week.&nbsp;<\/p>\n\n\n\n<p>Wegovy can help you lose weight by slowing your digestion, which makes you feel fuller longer after you eat.<\/p>\n\n\n\n<p>It can also alter hormones that impact appetite in a way that can result in you eating fewer calories, resulting in weight loss when paired with healthy lifestyle changes.<\/p>\n\n\n\n<p>Wegovy is in a class of medications called GLP-1 receptor agonists. These drugs appear to restore a hormone activation pattern more similar to lean patients, which helps aid in weight loss.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-about-mounjaro-tirzepatide\">About Mounjaro (Tirzepatide)<\/h2>\n\n\n\n<p>Mounjaro is the brand name for the drug tirzepatide, a medication used to treat type 2 diabetes. It\u2019s one of the <a href=\"https:\/\/blog.bensnaturalhealth.com\/diabetes-health\/diabetes-medications\/\" target=\"_blank\" rel=\"noreferrer noopener\">newer diabetes medications<\/a> on the market, with a recent approval by the United States Food and Drug Administration in 2022.<\/p>\n\n\n\n<p>According to <a href=\"https:\/\/investor.lilly.com\/news-releases\/news-release-details\/new-analyses-mounjarotm-tirzepatide-injection-treatment-adults\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">clinical trials<\/a> on Mounjaro, 87%-97% of participants taking it experienced both A1C reductions and weight loss.&nbsp;<\/p>\n\n\n\n<p>How does Mounjaro help you lose weight and lower blood sugar?<\/p>\n\n\n\n<p>Mounjaro is a dual GLP-1 receptor agonist and glucose-dependent insulinotropic polypeptide (GIP). You likely recognize the GLP-1 receptor agonist part (that\u2019s what Wegovy is!), but what is the GIP part?<\/p>\n\n\n\n<p>GIP is a hormone found in your intestinal tract (digestive system) and stands for gastric inhibitory polypeptide.&nbsp;<\/p>\n\n\n\n<p>GIP stimulates insulin release in the postprandial state (after you eat, when blood sugar levels rise) to help keep your blood glucose levels from getting too high.<\/p>\n\n\n\n<p>If your blood sugar levels are normal or low, GIP stimulates glucagon secretion. Glucagon is a hormone that helps raise your blood sugar levels and helps prevent hypoglycemia (low blood sugar).&nbsp;<\/p>\n\n\n\n<p>That means that GIP only stimulates insulin secretion when your blood sugar is rising, helping reduce the likelihood of having low blood sugar.&nbsp;<\/p>\n\n\n\n<p>However, the manufacturer of Mounjaro states that overall, Mounjaro helps to reduce glucagon levels.<\/p>\n\n\n\n<p>The other way Mounjaro works is through the GLP-1 receptor agonist route, which helps slow gastric emptying and boost satiety, similar to Wegovy.&nbsp;<\/p>\n\n\n\n<p>The dosing schedule for Mounjaro is 2.5 milligrams, 5 milligrams, 7.5 milligrams, 10 milligrams, 12.5 milligrams, or 15 milligrams in a weekly injection.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-wegovy-vs-mounjaro\">Wegovy vs Mounjaro<\/h2>\n\n\n\n<p>The below sections compare wegovy vs mounjaro (semaglutide vs tirzepatide), including uses, benefits, cost, effectiveness, side effects, and more.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-uses\">Uses<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-wegovy\">Wegovy<\/h3>\n\n\n\n<p>Unlike Mounjaro, Wegovy is meant to be used as a weight loss aid only &#8211; it\u2019s not meant to treat type 2 diabetes.&nbsp;<\/p>\n\n\n\n<p>This can be confusing since many GLP-1 receptor agonists are used to treat diabetes.<\/p>\n\n\n\n<p>The difference between Wegovy and many other GLP-1 receptor agonists for diabetes is that it received its FDA approval for weight loss, whereas the other GLP-1 receptor agonists are only approved to treat diabetes (with a potential to still cause weight loss).&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-mounjaro-nbsp\">Mounjaro&nbsp;<\/h3>\n\n\n\n<p>Mounjaro is meant to treat type 2 diabetes and isn\u2019t meant to be used as a <a href=\"https:\/\/blog.bensnaturalhealth.com\/diabetes-health\/mounjaro-weight-loss\/\" target=\"_blank\" rel=\"noreferrer noopener\">weight loss aid<\/a> for people without diabetes.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-differences\">Differences<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Wegovy is approved to treat weight loss in overweight adults without diabetes, whereas Mounjaro is approved to treat type 2 diabetes.<br><\/li>\n\n\n\n<li>Mounjaro is a dual GLP-1 receptor agonist and glucose-dependent insulinotropic polypeptide (GIP), while Wegovy is only a GLP-1 receptor agonist (no GIP).<br><\/li>\n\n\n\n<li>Mounjaro seems to elicit more significant weight loss at the maximum dose, but it isn\u2019t intended to be used for weight loss in people without diabetes like Wegovy is.<br><\/li>\n\n\n\n<li>Cost (Wegovy is more expensive than Mounjaro &#8211; more on that below).<br><\/li>\n\n\n\n<li>Wegovy is meant to be used in people with a BMI of 27 or higher, whereas there aren\u2019t any weight restrictions for Mounjaro.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-similarities\">Similarities<\/h2>\n\n\n\n<p><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Are approved to use in people aged 18 and older.<br><\/li>\n\n\n\n<li>Both are GLP-1 receptor agonists.<br><\/li>\n\n\n\n<li>Both are once-weekly injectable medications.<br><\/li>\n\n\n\n<li>Medications share similar side effects and risks.<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-effectiveness\">Effectiveness<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-wegovy-0\">Wegovy<\/h3>\n\n\n\n<p>A <a href=\"https:\/\/www.wegovy.com\/about-wegovy\/weight-loss-with-wegovy.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">study<\/a> was done on almost 2,000 overweight or obese adults without diabetes. Participants taking the full dose of Wegovy lost an average of 35 pounds over the 68-week study, which was about 15% of their starting body weight.&nbsp;<\/p>\n\n\n\n<p>Overall, 83% of people taking Wegovy lost at least 5% of their body weight.<\/p>\n\n\n\n<p>According to a <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8717485\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">2022 paper<\/a> from the Journal of Investigative Medicine, a review of ten studies concluded that Wegovy was \u201csuperior\u201d to other GLP-1 receptor agonists in reducing patients\u2019 body weight.<\/p>\n\n\n\n<p>Wegovy hasn\u2019t been studied in terms of its ability to lower blood sugar because it isn\u2019t meant to be used as a diabetes treatment.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-mounjaro-nbsp-0\">Mounjaro&nbsp;<\/h3>\n\n\n\n<p>As we mentioned earlier, studies have shown that 87%-97% of participants taking Mounjaro experienced both A1C and weight loss. But how does weight loss compare to Wegovy?<\/p>\n\n\n\n<p>According to a <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35658024\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">study<\/a>, participants taking Mounjaro lost just over 20% of their starting weight when taking the highest dose of 15 milligrams per week. Patients taking a lower dose of 5 milligrams per week lost 15% of their body weight, on average.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-cost-and-availability\">Cost and availability<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-wegovy-1\">Wegovy<\/h3>\n\n\n\n<p>According to GoodRx, four prefilled pens with 2.4 milligrams each (the maximum dose) of Wegovy cost around $1400 out of pocket (not counting any insurance or prescription drug benefits), which would last for four weeks (around one month) of weekly treatment.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-mounjaro-nbsp-1\">Mounjaro&nbsp;<\/h3>\n\n\n\n<p>Also, according to GoodRx, four pens of the 15-milligram dose the max dose) of <a href=\"https:\/\/blog.bensnaturalhealth.com\/diabetes-health\/mounjaro-cost\/\" target=\"_blank\" rel=\"noreferrer noopener\">Mounjaro cost<\/a> around $1000-$1050 out of pocket.<\/p>\n\n\n\n<p>That means that Wegovy is more expensive when compared to Mounjaro by around $250-$300 every four weeks.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-side-effects-and-risks\">Side effects and risks<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-wegovy-2\">Wegovy<\/h3>\n\n\n\n<p>The most common potential side effects of Wegovy include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Nausea<\/li>\n\n\n\n<li>Diarrhea<\/li>\n\n\n\n<li>Vomiting<\/li>\n\n\n\n<li>Constipation<\/li>\n\n\n\n<li>Abdominal (stomach) pain<\/li>\n\n\n\n<li>Headache<\/li>\n\n\n\n<li>Fatigue<\/li>\n\n\n\n<li>Dyspepsia (indigestion)<\/li>\n\n\n\n<li>Dizziness<\/li>\n\n\n\n<li>Abdominal distension<\/li>\n\n\n\n<li>Belching<\/li>\n\n\n\n<li>Hypoglycemia (low blood sugar) in patients with type 2 diabetes<\/li>\n\n\n\n<li>Flatulence<\/li>\n\n\n\n<li>Gastroenteritis (inflammation of the stomach and intestines)<\/li>\n\n\n\n<li>Gastroesophageal reflux disease (GERD), most commonly referred to as heartburn<\/li>\n<\/ul>\n\n\n\n<p>More rarely, Wegovy might cause more serious side effects and health issues. The most notable potential serious side effects for Wegovy (and other GLP-1 receptor agonists) are below.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Wegovy causes thyroid tumors and thyroid cancer in rodents, and it\u2019s unknown if it will likely cause thyroid tumors in humans. You should avoid taking Wegovy if you have a history (personal or family) of medullary thyroid carcinoma (MTC), a type of thyroid cancer.&nbsp;<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>It\u2019s unknown if Wegovy is safe to take if you have a history of pancreatitis. If you have <a href=\"https:\/\/blog.bensnaturalhealth.com\/diabetes-health\/pancreatitis-symptoms\/\" target=\"_blank\" rel=\"noreferrer noopener\">symptoms of pancreatitis<\/a>, you should discontinue Wegovy and consult your healthcare provider.<br><\/li>\n\n\n\n<li>Wegovy might cause gallbladder problems in some people.<br><\/li>\n\n\n\n<li>Vision changes have been reported while taking Wegovy.<br><\/li>\n\n\n\n<li>Dehydration from persistent nausea and vomiting can lead to kidney problems.<br><\/li>\n\n\n\n<li>Hypoglycemia (low blood sugar), especially if you\u2019re taking other medications for diabetes, such as insulin or sulfonylureas.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Allergic reactions to Wegovy or its ingredients.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-mounjaro\">Mounjaro<\/h3>\n\n\n\n<p>Because Mounjaro is also a GLP-1 receptor agonist, it carries similar potential side effects and risks as Wegovy.&nbsp;<\/p>\n\n\n\n<p>Some of the most common side effects of Mounjaro are:<\/p>\n\n\n\n<p>The more common side effects of Mounjaro are generally minor (not life-threatening) and include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Nausea<\/li>\n\n\n\n<li>Diarrhea<\/li>\n\n\n\n<li>Decreased appetite<\/li>\n\n\n\n<li>Vomiting<\/li>\n\n\n\n<li>Constipation<\/li>\n\n\n\n<li>Indigestion<\/li>\n\n\n\n<li>Stomach (abdominal) pain<\/li>\n<\/ul>\n\n\n\n<p>The rare but serious potential side effects of Mounjaro are similar to Wegovy:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Allergic reactions to Mounjaro or its ingredients<\/li>\n\n\n\n<li>Changes in your vision (worsening of diabetic retinopathy can occur with drastic blood sugar changes)<\/li>\n\n\n\n<li>Gallbladder problems<\/li>\n\n\n\n<li>Hypoglycemia (low blood sugar), especially if you\u2019re taking other medications for diabetes, such as insulin or sulfonylureas<\/li>\n\n\n\n<li>Kidney problems due to dehydration<\/li>\n\n\n\n<li>Low blood sugar (hypoglycemia)<\/li>\n\n\n\n<li>Pancreatitis<\/li>\n\n\n\n<li>Severe stomach problems<\/li>\n\n\n\n<li>Thyroid carcinomas (tumors) &#8211; there is a black box warning from the FDA due to the chance that Mounjaro (and other GLP-1 receptor agonist drugs) might cause thyroid tumors<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>Drug<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>Medication type<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>Intended use<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>Cost<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>Dose range<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>Effectiveness (weight loss)<\/strong><\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">Wegovy<\/td><td class=\"has-text-align-center\" data-align=\"center\">GLP-1 receptor agonist<\/td><td class=\"has-text-align-center\" data-align=\"center\">Adults 18+ with a BMI of 27 or greater<\/td><td class=\"has-text-align-center\" data-align=\"center\">$1400 per 4 weeks for max dose<\/td><td class=\"has-text-align-center\" data-align=\"center\">2.4 mg per week is the goal (max dose &#8211; injection)<\/td><td class=\"has-text-align-center\" data-align=\"center\">15% of body weight at a max dose (2.4 milligrams per week)<\/td><\/tr><tr><td class=\"has-text-align-center\" data-align=\"center\">Mounjaro<\/td><td class=\"has-text-align-center\" data-align=\"center\">Dual GLP-1 receptor agonist and glucose-dependent insulinotropic polypeptide (GIP).<\/td><td class=\"has-text-align-center\" data-align=\"center\">Adults 18+ with type 2 diabetes<\/td><td class=\"has-text-align-center\" data-align=\"center\">$1050 per 4 weeks for max dose<\/td><td class=\"has-text-align-center\" data-align=\"center\">2.5-15 mg per week (injection)<\/td><td class=\"has-text-align-center\" data-align=\"center\">Over 20% of body weight at a max dose (15 milligrams per week)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-can-you-take-wegovy-and-mounjaro-together\">Can you take Wegovy and Mounjaro together?<\/h2>\n\n\n\n<p>No. Because they are both GLP-1 receptor agonists, Wegovy and Mounjaro should not be used together. Taking them together could result in more severe side effects and potential risks.<\/p>\n\n\n\n<p>If you want to switch from Wegovy to Mounjaro or vice-versa, consult your healthcare provider on the best way to make the switch.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-conclusion\">Conclusion<\/h2>\n\n\n\n<p>Wegovy is a GLP-1 receptor agonist medication approved for weight loss in adults with a BMI over 27.&nbsp;<\/p>\n\n\n\n<p>Mounjaro is a dual GLP-1 receptor agonist and glucose-dependent insulinotropic polypeptide (GIP) medication used to treat type 2 diabetes, but it can also result in significant weight loss.<\/p>\n\n\n\n<p>Because they are both GLP-1 receptor agonists, Wegovy and Mounajro share similar side effects and potential risks.<\/p>\n\n\n\n<p>The main differences between Wegovy vs Mounjaro are their intended uses, mechanism of action, effectiveness, and cost.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Explore More<\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/blog.bensnaturalhealth.com\/diabetes-health\/wegovy-alternatives\/\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"217\" src=\"https:\/\/blog.bensnaturalhealth.com\/wp-content\/uploads\/2022\/11\/wegovy-alternatives-1024x217.jpg\" alt=\"wegovy alternatives\" class=\"wp-image-38070\" srcset=\"https:\/\/www.bensnaturalhealth.com\/blog\/wp-content\/uploads\/2022\/11\/wegovy-alternatives-1024x217.jpg 1024w, https:\/\/www.bensnaturalhealth.com\/blog\/wp-content\/uploads\/2022\/11\/wegovy-alternatives-300x64.jpg 300w, https:\/\/www.bensnaturalhealth.com\/blog\/wp-content\/uploads\/2022\/11\/wegovy-alternatives-768x163.jpg 768w, https:\/\/www.bensnaturalhealth.com\/blog\/wp-content\/uploads\/2022\/11\/wegovy-alternatives.jpg 1180w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<p><a href=\"https:\/\/blog.bensnaturalhealth.com\/diabetes-health\/wegovy-alternatives\/\" target=\"_blank\" rel=\"noreferrer noopener\">Alternatives To Wegovy For Weight Loss<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>GLP-1 receptor agonist medications have been all over the news lately.&nbsp; Not only can GLP-1 receptor agonists help lower blood sugar levels in people with type 2 diabetes, but they\u2019re wildly popular for their potential weight loss benefits in people without diabetes, too. Certain GLP-1 receptor agonists are approved to use for weight loss in [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":40169,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[],"health_topic":[125,145],"class_list":["post-40168","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","health_topic-diabetes-health","health_topic-diabetes-medication"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Wegovy vs Mounjaro: Benefits, Weight Loss, Side Effects, Cost<\/title>\n<meta name=\"description\" content=\"We compare wegovy vs mounjaro (semaglutide vs tirzepatide), including uses, benefits, cost, availability, effectiveness, weight loss, side effects, 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