Family History of Prostate Cancer? When To Get Checked

Prostate cancer is an abnormal and uncontrolled growth of the prostate cells. 

The causes of most cancers are not known. But, several risk factors play a role in getting these cancers.

A positive family history of prostate cancer is one of the major risk factors for the disease. 

Men whose fathers or brothers have had prostate cancer are more than twice as likely to develop prostate cancer.

But what does a positive family history mean exactly, and how does it affect you? 

We discuss these and many other related questions in this article.

How does family history affect your risk of prostate cancer?

You are two and a half times more likely to get prostate cancer if your father or brother has a history of it.

Having this risk factor does not mean that you will definitely have prostate cancer; it means you have an increased chance of getting it. 

If more than one family member has it, especially if they were diagnosed young, your risk may be even higher.

Studies have shown that you can inherit high-risk and prostate cancer-susceptible genes from your family. 

Up to 10% of prostate cancer cases may be caused by prostate cancer susceptible genes.

Other risk factors for prostate cancer include:

  • Aging – The older you get, the higher your risk of having prostate cancer. The risk increases rapidly after the age of 50.
  • Race – While any man of any race can develop prostate cancer, it is more common in black men.
  • Obesity – It may increase your risk of getting more aggressive forms of prostate cancer.
  • Chemical exposure – exposure to some hazardous substances may increase your risk of prostate cancer. Studies have found links between prostate cancer and exposure to arsenic. Some studies have also found a possible association between prostate cancer and a chemical called Agent Orange, which was widely used during the Vietnam War.

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When should I get prostate cancer screening if I have a family history?

The American Urological Association (AUA) recommends the following guidelines:

  • Annual PSA screening from as early as 40 years old for men with a high risk of prostate cancer. These include:
    • People with a positive family history of prostate cancer.
    • Those with a family history of other malignancies such as breast cancer, ovarian cancer, and Lynch syndrome.
    • Men of African descent.
    • Men who have been exposed to hazardous organic substances.
  • Screening every two to four years for men who have low risk from 55 years of age.

PSA screening is not recommended by the AUA for men less than 40 years old.

Ben’s Advanced Prostate Cancer Risk Assessment

Ben’s Advanced Prostate Cancer Risk Assessment (APCRA) is a natural prostate cancer screening that consists of non-invasive blood tests and specialized color Doppler scans. 

After this testing, you will receive a thorough, 3-hour consultation from a Naturopathic Physician, who is also a Professor of Urology, who will walk you through the results of his assessment and explain every aspect and each option available to you, while also answering any questions that you may have. 

The greatest benefits of the APCRA are that it is non-invasive, does no damage, and does not close off any avenues for future treatment.

To book our Advanced Prostate Cancer Risk Assessment, please call our customer service team at +1-888-868-3554, who will be happy to assist you and offer any further information.

What is the difference between hereditary and familial prostate cancer?

Familial and hereditary prostate cancer are terms used to describe how prostate cancer may occur in families.

Familial prostate cancer describes situations in which prostate cancer runs in a particular family. This is thought to be a result of both shared genes and shared environmental factors and lifestyle habits.

Hereditary prostate cancer (HPC) is a specific form of familial prostate cancer in which a person with HPC inherits the susceptible gene from a relative.

In familial prostate cancer, there may be a family history where:

  • Two family members (first-degree) had prostate cancer sometime in their lives.
  • Or, one first-degree relative and two or more second-degree relatives had the disease at some point in their lives.

In hereditary prostate cancer, there is a stronger family history with one of the following:

  • Three or more first-degree relatives who had the disease.
  • Three generations in a row of relatives who were diagnosed with prostate cancer.
  • Two or more first-degree relatives who were diagnosed with the disease at a young (less than 55 years of) age.

Is familial prostate cancer more aggressive?

Some studies suggest that familial prostate cancer (including HPC) may be more aggressive than sporadic cancers and may affect the outcome of treatment. This means that if you have a family history of prostate neoplasm, you may be at a higher risk of having aggressive disease.

However, more studies are required to determine how aggressive a genetic predisposition can make prostate cancer.

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What is the ICD-10 code for family history of prostate cancer?

ICD 10 (International Classification of Diseases, Tenth Revision) is a coding guideline designed by the World Health Organization (WHO). 

It is used to classify different diseases in a standard manner. Each disease has its unique code based on the individual characteristics of each patient. 

The code includes letters and numbers that represent:

  • The part of the body affected
  • The personal history
  • Family history
  • Presence of metastasis (in case of neoplasms)
  • The treatment modality you received (chemotherapy, radiotherapy, surgery, etc.)
  • In-patient admission

The code summarizes your diagnosis for your doctor. Just by looking at the numbers and letters, they can get a lot of information about your condition – including your family history.

For a family history of malignant neoplasm, including prostate cancer, you would typically use the code Z80.42.


  • Prostate cancer is a type of cancer that affects the prostate, which is a small walnut-shaped organ found in males. 
  • Like many other cancers, the exact cause of prostate cancer is not known. However, some factors increase the risk of getting the disease.
  • A positive family history is one risk factor for prostate cancer. If you have one or more first-degree relatives who had prostate cancer, then you have a positive family history. 
  • This is an important detail you must tell your doctor. You need to get screened at an earlier age and with more frequency if you have this history.

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Our Natural & Non-Invasive Advanced Prostate Cancer Risk Assessment (APCRA).


  1. National Cancer Institute. Genetics of Prostate Cancer (PDQ®)–Health Professional Version.
  2. Bhattacharya P, McHugh TW. Lynch Syndrome. [Updated 2023 Feb 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-.
  3. Yang Y, McDonald AC, Wang X, Pan Y, Wang M. Arsenic exposures and prostate cancer risk: A multilevel meta-analysis. J Trace Elem Med Biol. 2022 Jul;72:126992. doi: 10.1016/j.jtemb.2022.126992. Epub 2022 May 5. PMID: 35550984.
  4. Ansbaugh N, Shannon J, Mori M, Farris PE, Garzotto M. Agent Orange as a risk factor for high-grade prostate cancer. Cancer. 2013 Jul 1;119(13):2399-404. doi: 10.1002/cncr.27941. Epub 2013 May 13. PMID: 23670242; PMCID: PMC4090241.
  5. Jain MA, Leslie SW, Sapra A. Prostate Cancer Screening. [Updated 2023 Oct 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-.
  6. Potter SR, Partin AW. Hereditary and familial prostate cancer: biologic aggressiveness and recurrence. Rev Urol. 2000 Winter;2(1):35-6. PMID: 16985733; PMCID: PMC1476098.

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