How to Tell When Your Ozempic Pen is Empty

Managing diabetes often involves using medications and tools, and one tool that comes in handy is the Ozempic pen (Semaglutide). 

Ozempic, or semaglutide, is a medication frequently prescribed to help control type 2 diabetes. 

Using the Ozempic pen can be a method of administering this medication. 

It’s important to track when the pen runs out to manage diabetes properly.

Keep reading to find out how to know when your ozempic pen is empty, including signs to spot and tips to check if you have any medication left.

Signs of an empty Ozempic pen (Semaglutide)

1) Reduced dosage

When your Ozempic pen starts running empty, you might notice that your dosage with each injection becomes less than you’re used to. 

This signals that it’s time to check the pen and consider getting a replacement.

2) Difficulty dialing the dose

An empty Ozempic pen can make it harder to dial in the dosage. If the dose dial isn’t moving smoothly or doesn’t align with your dosage, it could indicate that the pen is running low.

3) Can’t see any visible medication

If you inject Ozempic and there’s no medication in the pen window, the Ozempic pen has likely either run out or is close to being empty.

4) Poor blood sugar control

If you’ve been consistently following your dosage and dietary guidelines, but your blood sugar levels remain high, it could be a sign that your Ozempic pen is empty and not providing enough medication.

By paying attention to these signs, you can stay proactive in ensuring you have a supply of medication from your Ozempic pen.

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How to check if your Ozempic pen is empty

Here’s a guide on how to check if your Ozempic pen (Semaglutide) is empty to ensure you’re not caught off guard by running out of the medication:

1) Hold the pen upright 

Hold the pen upright with the needle pointing and the dose window facing you.

2) Look Through the Dose Window 

Take a look through the window of the pen. If you can see medication inside, it means it’s not empty. If there’s no medication left, it’s time to replace the pen.

How do you know how much medication is left in an Ozempic pen? 

Determining the amount of medication left in an Ozempic pen isn’t possible. 

You can estimate how much medication is left based on your prescribed dosage and how many doses you’ve already taken. 

Keeping track of your injections will give you an idea of how a typical pen lasts for you.

Can you reuse an empty Ozempic pen?

No, it is not recommended to reuse an Ozempic pen. The pen is specifically designed for single-use injections. 

Attempting to reuse Ozempic may compromise the sterility of the medication and increase the risk of infection.

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What should I do if my Ozempic injection has run out?

If you discover that your Ozempic pen is empty, follow these steps:

  1. Dispose of the pen: Safely dispose of the pen according to your healthcare provider’s instructions for medical waste disposal.
  2. Get a replacement Ozempic pen: If you haven’t already, contact your healthcare provider or pharmacist for an Ozempic pen. Ensure that you have a replacement before your scheduled dose.
  3. Monitor your blood sugar levels: Keep an eye on your blood sugar levels after replacing the pen to ensure you receive the dosage and maintain well-controlled levels.


Proper diabetes management is essential for maintaining good health, and knowing when your Ozempic pen is empty is a crucial aspect of that management. 

By staying aware of the signs of an empty pen and checking the dose window regularly, you can ensure that you’re consistently receiving the prescribed medication to help control your blood sugar levels.

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  1. Khan MAB, Hashim MJ, King JK, Govender RD, Mustafa H, Al Kaabi J. Epidemiology of Type 2 Diabetes – Global Burden of Disease and Forecasted Trends. J Epidemiol Glob Health. 2020. 
  2. [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Semaglutide (Ozempic) for the treatment of type 2 diabetes: Overview. 2019 Feb 28. 
  3. Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, McGowan BM, Rosenstock J, Tran MTD, Wadden TA, Wharton S, Yokote K, Zeuthen N, Kushner RF; STEP 1 Study Group. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021 Mar. 

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