What To Avoid When Taking Byetta: Drugs, Alcohol, Food

If you’re taking Byetta (Exenatide) for diabetes, you may wonder if you need to make any changes while taking this medication.

Keep reading to learn about what to avoid when taking Byetta, with some important exenatide warnings and drug interactions to be aware of.

Always make sure you speak with your doctor or pharmacist about all the medications you are taking before starting a new one. 

1) Alcohol

Alcohol consumption is not recommended when taking Byetta. Alcohol can affect blood sugar levels, which can result in hypoglycemia (low blood sugar levels) or hyperglycemia (high sugar levels). 

2) Don’t Take Exenatide With Food

Avoid taking Byetta with food. Taking Exenatide with food can reduce its absorption and affect the results. You should inject Byetta up to an hour before eating a meal.

3) Certain Herbal Supplements

If you are taking any herbal supplements, it’s important to talk to a health professional to determine if they may cause an interaction with Byetta. 

4) Certain Oral Antibiotics

Since Byetta delays gastric emptying, it can affect the absorption of antibiotics, meaning it may cause a delay in the antibiotic treatment. 

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5) Diabetes Medications

Taking other anti-diabetic medications with Byetta can increase the risk of side effects, such as hypoglycemia. 

6) Warfarin

Taking Byetta can affect how much warfarin your body absorbs, meaning it can make you absorb too much or too little. 

7) Birth Control Pills

Taking your birth control pill near Byetta can delay its absorption, meaning it can reduce its effectiveness. 

8) Beta-Blocker Medications

They can increase the risk of Byetta’s side effects, such as a fast heartbeat or dizziness. 


  • Taking Byetta (Exenatide) for diabetes requires careful consideration of various factors to ensure its effectiveness and your overall well-being. 
  • There are certain medications or foods you may need to avoid when taking Byetta due to potential interactions.
  • Always tell your doctor or pharmacist all the medications and supplements you are taking before starting a new medication.
  • Prioritizing open communication with your healthcare team and adhering to their guidance will contribute significantly to the success of your diabetes management plan.

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  1. Bond A. Exenatide (Byetta) as a novel treatment option for type 2 diabetes mellitus. Proc (Bayl Univ Med Cent). 2006 Jul;19(3):281-4. doi: 10.1080/08998280.2006.11928181. PMID: 17252050; PMCID: PMC1484540.
  2. Exenatide (Byetta) for type 2 diabetes. Med Lett Drugs Ther. 2005 Jun 6;47(1210):45-6. PMID: 15933616.
  3. BYETTA® (exenatide) injection, for subcutaneous use and should be used with caution in patients with renal transplantation. Initial U.S. Approval: 2005.
  4. Guyton J, Jeon M, Brooks A. Glucagon-like peptide 1 receptor agonists in type 1 diabetes mellitus. Am J Health Syst Pharm. 2019 Oct 15;76(21):1739-1748. doi: 10.1093/ajhp/zxz179. PMID: 31612934.

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