What Foods Provide Calcium D-Glucarate?

If you ever thought about boosting your liver metabolism and balancing out the excess steroid hormones in the system, you’ve heard of the Calcium D Glucarate. Many foods calcium d glucarate and are good for your health.

It’s a popular addition to calcium supplements and meal plans for those looking to improve their overall health. 

The question is, what makes D glucarate so special? How can it benefit men’s health? We decided to take a closer look at this particular chemical and its effect on the human body. This is a detailed guideline for this calcium. But, first, let’s start with the basics.

What is Calcium D Glucarate?

The glucarate is a naturally occurring chemical in the body. It is the calcium form of D glucaric acid – a calcium salt, created by mixing glucaric acid and calcium. 

Calcium glucarate is primarily used for avoiding specific types of cancer. Since it could reduce the excess estrogen levels in the human body, it could strengthen the defense mechanism to fend off disease and promote breast health. 

How can this calcium benefit men’s health?

Researchers have studied the effects of glucarate for many years now. While the number of scientific studies is limited, some sources believe this calcium could be immensely beneficial for men’s health.

Here are some of its most beneficial effects that could benefit the male population.

1) Prostate Cancer

Prostate cancer is the second primary cause of death in American men. The problem is that 1 out of 9 men will experience this type of cancer at least once in their lifetime, stated the Urology Care Foundation. In 2019, almost 191,000 men were diagnosed with this specific cancer condition. 

When the prostate is affected, cancer could spread to the other tissues and grow into a tumor-exposing men to even more damage. 

According to a 2002 report, glucarate could inhibit the beta-glucuronidase. This enzyme belongs to the family of enzymes that breakdown the complex carbs. By inhibiting the beta-glucuronidase, the chemical could have the potential to stabilize the elevated hormone levels and keep the system on track.

On top of that, glucarate is believed to promote detoxification by removing the steroids and toxins from the system, including other agents that cause cancer. It can help with full detoxification, which is healthy for a system that is vulnerable to cancer. As well as the phase 2 detoxification process. 

But, most people don’t realize that the estimated effects from this chemical come from the D glucarate, not the calcium. 

Glucuronidation is one of the main pathways that take part in the second detoxification phase. They help the endogenous and environmental compounds, like the carcinogens and drugs to leave the system.

When paired with vitamins D, A, E, and C, people can experience more beneficial effects. They could reduce their odds of developing various types of cancer, even in bodies at a risk of cancer. 

2) Testosterone levels

Older men experience a steady decline in testosterone levels. When they hit 30, their levels start to drop around 1% each year. In their 50s, testosterone levels decrease by 5%. But, once they reach 80 years of age, these levels will drop by a staggering 20%. 

Glucarate could be the key to solving the problem. Since it’s believed to reduce the estrogen levels, it can remove the liver’s excess hormones. Glucarate intake could help prevent estrogen dominance and boost prostate health. 

With the reduced risk of estrogen-related cancer, the body could be able to combat poor testosterone production. This can be a highly beneficial option for the older population.

3) Liver detox

When this calcium is consumed orally, the body will metabolize it and turn it into glucaric acid. This is what experts refer to as the active form of D glucarate. The body creates it completely naturally without the need for outside stimulants. But, the glucaric acid, alone, can’t be used as a supplement. 

To determine the amount of calcium in a specific product, you would need to check out the dietary supplement’s elemental calcium. It can help point out the various calcium molecules, like calcium citrate, calcium carbonate, etc. 

This type of calcium in supplements is mainly used to boost the liver detox process. Typical CDG detoxes take about 5 hours to complete, while with glucarate, the effects can be noticed in just 1 hour. The natural color variation could occur in this kind of supplement.

The reason for that is relatively simple. The acid will bind itself to the stomach toxins and stimulate the intestines to remove them through the urine. The acid will then move around the system to release and scavenge for some more toxins. 

This can improve liver function and help the metabolism work properly. While it might sound unnatural, everything the glucarate does is entirely normal. 

Since the body can produce its own glucarate, the chemical won’t take a toll on the body’s natural cleansing mechanisms. Instead, it can promote the system to do complete detoxification all on its own. 

In other words, all the toxins, including the environmental toxins, can be flushed out. This will help the body stay on track and function healthily. Plus, a glucarate supplement often contains cellulose, which can be an excellent fiber source for the body. 

4) Reduce man boobs & inability to lose fat

As men get older, they tend to experience drastic changes in their bodies. The increased beta-glucuronide levels start to affect the estrogen receptors. The estrogen that should have been removed from the body can bind itself to more receptors. 

Therefore, resulting in constant tissue growth. For men, these effects start to impact their bodies. It becomes difficult for them to lose fat, and they start developing “man boobs” or increased chest swelling. 

The estrogen receptors’ constant imbalance is the number one cause for mood changes, infertility, and health issues in both men and women. 

Based on an animal study, this calcium can reduce the estrogen receptor numbers by 48%. At the same time, serum estrogen levels could only affect the receptors by 23%. Although the research is limited, glucarate could help people keep a normal hormone balance.  

5) Balances the cholesterol

Over 95 million American adults are experiencing high cholesterol levels. This is a huge issue for those living with a metabolic condition. Unstable cholesterol levels can take a toll on heart health and cause a range of different cardiovascular complications. 

When the cholesterol is out of balance, the damaged and stressed cells in the human body can’t rely on the cholesterol anymore to repair themselves. This slows down the damaged tissue repair process and leaves the body vulnerable to stress and limited blood flow.

To restore optimal health, you will need to put the LDL cholesterol under control. Glucarate can help. 

Since the body metabolizes it into glucaric acid, it can reduce the beta-glucuronidase production rate. The gut bacteria can return to normal, and the body can synthesize the cholesterol properly. 

An animal study showed that D glucarate could reduce the total cholesterol from 12% to 15%, and the LDL cholesterol from 30% to 35%. Also, it may decrease the triglyceride number by a maximum of 43%. 

The key effect in the acid lies in its stress-reducing properties. Glucarate can reduce the stress on the liver, particularly the one caused by elevated cholesterol levels. 

6) Perfect for diets high in protein

Protein-high diets are all the rage right now. Countless fitness enthusiasts are focusing on consuming meals high in fat and protein to build muscle mass. Our kidneys and livers need that protein to get rid of the dangerous byproducts in the human system, like ammonia, for example.

But, there is a limit to how many toxins the body can handle. The human system has to focus on multiple factors, like defending the organs from air pollutants, invading pathogens, xenoestrogens, etc. So, technically, it has little room to deal with the protein.

With the constant pollution, it is important to incorporate something else that can boost the body to remove the byproducts naturally. Glucarate can help flush out any toxin from the system, speed up the metabolism, and help the body fend off the byproducts. All of these benefits could be useful for a high protein diet.

What’s the Right Dosage?

The proper dose for glucuronic acid highly depends on a person’s health state, age, and other conditions. Right now, there is no scientifically-approved dosage that will perfectly fit everyone. If you want to include a dietary supplement with glucarate, it would be best to first consult with your physician. They can help you determine the right dose that will work for your body. 

10 Calcium D Glucarate foods to add to your diet

Although glucarate is often prescribed, people can take it from foods. Plenty of foods are packed with calcium d glucarate acid. The good thing is, the majority of these sources are cruciferous vegetables and fruits. That means you will be consuming meals packed with nutrients, minerals, and vitamins. 

Increasing the glucarate intake from foods can be beneficial for the body. It’s much easier to regulate the dose and provide the system with the necessary dietary needs. Here is a list of some of the best calcium d glucarate foods you can add to your meal plans.

  1. Brussel sprouts

  2. Oranges

  3. Squash

  4. Cabbage

  5. Apples

  6. Broccoli

  7. Grapefruit

  8. Kale

  9. Bean Sprouts

  10. Cauliflower

Broccoli and apples have as much as 3.5g/kg of this particular chemical. Compared to lettuce and grapes, that is a huge gap compared to the 0.1g/kg you are getting from lettuce and grapes. With vegetables and fruits such as these, you can make the most of the D glucaric acid and support the body’s natural defense mechanisms. 

This can be useful when boosting the detoxification process, removing the steroid hormone, and the excess toxins. When the glucarate gets to the GI tract, it will be metabolized into three distinct compounds. 

The most active of them is the D glucagon (1.4-lactone). This is an enzyme that the colonic bacteria can produce. Its main purpose is to break apart the probable toxins and eliminate them from the body through a natural liver detoxification process. 

So feel free to include any of the options here as a practical ingredient in your meal. That way, you can take the food to a whole new level and promote normal cellular function. 

Interactions with medication, supplements, & foods

If you want to take calcium glucarate in the form of a supplement, you should know about the possible interactions. Currently, there are no known interactions when taking a glucarate supplement with medication. 

However, many medicines, particularly those for restoring hormonal balance, get metabolized in the liver. They bind themselves to the glucuronic acid. Therefore, there is a chance that consuming a glucarate supplement might increase the odds of eliminating drugs from the system. This will reduce their effectiveness. 

Experts advise people to talk to their doctor before adding the calcium supplement to their diet. Because the research is still underway, there is a chance some unknown interactions might exist. So, it’s very important to get a professional opinion when incorporating new supplements together with drugs.


Given the lack of sufficient research and human trials, it’s hard to tell if glucarate could be useful for preventing cancer completely. With the existing research, it’s easy to see that this chemical has some amazing potential. But, if you plan to incorporate calcium d glucarate foods into your diet, you should consult with a doctor first. They can help you plan the meals that will best fit your needs.

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  1. National Library of Medicine. (2002). Calcium-D-glucarate. Retrieved from: https://pubmed.ncbi.nlm.nih.gov/12197785/
  2. Margaret Hanausek. (2003). Detoxifying Cancer Causing Agents to Prevent Cancer. Sage Journals. Retrieved from: https://journals.sagepub.com/doi/10.1177/1534735403002002005
  3. Urology Care Foundation. (2018). What is Prostate Cancer. The Official Foundation of the American Urological Association. Retrieved from: https://www.urologyhealth.org/urologic-conditions/prostate-cancer
  4. Rundi Hutter Epstein. (2018). The Highs and Lows of Testosterone. The New York Times. Retrieved from: https://www.nytimes.com/2018/03/27/well/live/testosterone-supplements-low-t-treatment-libido.html
  5. Joseph Pritchard. (2018). The Effects of Progesterone & Estrogen in Men. Retrieved from: https://healthfully.com/the-effects-of-progesterone-estrogen-in-men-6166637.html
  6. Dave Asprey. (2020). 8 Natural Ways to Treat PMS and PMDD. Retrieved from: https://blog.daveasprey.com/natural-ways-treat-pms-pmdd/
  7. Center for Disease Control and Prevention. High Cholesterol Facts. Retrieved from: https://www.cdc.gov/cholesterol/facts.htm
  8. Zbigniew Walaszek. (1996). D-Glucaric acid content of various fruits and vegetables and cholesterol-lowering effects of dietary D-glucarate in the rat. Science Direct. Retrieved from: https://www.sciencedirect.com/science/article/pii/0271531796000450
  9. WebMD. Calcium D-glucarate. Retrieved from: https://www.webmd.com/vitamins/ai/ingredientmono-136/calcium-d-glucarate
  10. Peace Health. Calcium D-glucarate. Health Information Library. Retrieved from: https://www.peacehealth.org/medical-topics/id/hn-2820001#hn-2820001-interactions

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