Yohimbine Supplements for ED: Can They Help?

About 30 million American men have erectile dysfunction. With the U.S. having the highest rates of self-reported ED cases, there is a growing interest in ED supplements. 

People are constantly on the lookout for simpler and more effective erectile dysfunction treatments. Latest reports show that the global market for ED supplements is expected to have over 9% growth from 2019 to 2023.

One supplement that recently gained momentum is Yohimbine. There is a lot of speculation that Yohimbine can help with erectile dysfunction

The question is, how effective can it really be? Can people use Yohimbine as a safe male enhancement supplement? How long will it take for Yohimbine to improve blood flow and take care of the erection problem? 

Here we will answer all the questions for you. We compiled a statistical analysis of Yohimbine and its impact on the human body. 

Yohimbine – What Is It and How Does It Work for ED?

Men have been using this herbal supplement for centuries. Praised for its aphrodisiac effect, Yohimbine is used in countless over-the-counter ED supplements. According to experts, the bark of the Yohimbine tree is believed to promote sexual performance. 

It may also help with:

  • Weight reduction

  • Erectile dysfunction

  • Athletic performance

  • Angina

In the form of a supplement, Yohimbine comes in tablets or capsules. The product works by blocking the alpha 2 adrenergic receptors, which are known for hindering erections. Some reports indicate that Yohimbine has the potential to enhance nitric oxide release.

As a result, it can dilate the blood vessels, amplify blood flow, and thus fix the erection issues. But, more research is necessary to study its full impact on the human body. 

Yohimbine Supplements for ED: Are They Effective?

One double-blind clinical trial studied the therapeutic effect of Yohimbine hydrochloride on 82 patients with erectile dysfunction. After a month of ED treatment with a maximum dose of 42 mg a day, the drug showed a beneficial impact. 

Roughly 14% of patients fully restored and maintained their erections by the end of the trial. Around 20% had a partial response, while 65% had no improvement after taking the drug. Maximum effects took 2 to 3 weeks to manifest. These reports are encouraging due to the few side effects.

Another study showed that a Yohimbine drug is superior to placebo for erectile dysfunction treatment. It is seen as a reasonable therapeutic option and can be used before trying other ED drugs. Another research also showed similar results.

Based on the reports, there are less than a dozen controlled studies on Yohimbine as an ED pill. But, research on Yohimbine and erectile dysfunction in people are limited. 

Most lack sufficient evidence on erectile function. Plus, the different administration methods make it difficult to predict its exact result. Yet, it has some potential as a male enhancement treatment option.

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Other Uses of Yohimbine Supplements

Yohimbine has many uses. This dietary supplement may not be as potent as its medicinal counterpart but could prove useful for various issues. 

Other than being a possible sexual enhancement tool, it can also be used for: 

  • Blood sugar control – Patients with type 2 diabetes triggered by a mutation in the alpha(2A)-AR gene enhanced their insulin production with Yohimbine treatment. They also reduced their blood sugar levels compared to those who received placebo treatment.

  • Blood clotting – Yohimbine could reduce blood clotting. However, taking the product together with any medication that reduces clotting could lead to increased bleeding and bruising. 

  • Saliva secretion – People who take antidepressant medication can use the active ingredient of Yohimbine to ease the symptoms of dry mouth. But, more research is necessary to study its impact. 

  • Memory – Yohimbine leads to better memory consolidation in depressed patients. The enhanced memory function can help those with major depressive disorder. With more studies, scientists will be able to evaluate its potential beneficial properties.

Safety Considerations

Talk to a doctor before you try to use any pill or sexual enhancement supplements. There is a strong connection between ED and heart disease. So, you want to be extra careful when trying different treatment methods.

Your doctor will suggest the safest treatment for avoiding side effects. Overall, Yohimbe supplements can trigger unwanted reactions. These include:

  • Anxiety

  • High blood pressure

  • Stomach issues (nausea and diarrhea)

  • Increased or irregular heartbeat

  • Dizziness

  • Sleeplessness

  • Urinary troubles

Those who experience adverse reactions to Yohimbe supplements often need medical treatment. If you notice a reaction to the pill you are taking, avoid using the product completely. Consult with a healthcare expert if the male enhancement pills don’t curb the ED symptoms. 

Depending on what you are dealing with, you might need more rigorous ED treatment. If nothing else works, some people use a penile implant or penile prosthesis to enhance sexual function. Others prefer prescription drugs to manage their sexual health.

Other ED Supplements

Some vitamins and herbal remedies are better at easing erectile dysfunction than others. Vitamin D is one of the most studied vitamins in ED treatment. According to experts, there is a clear link between Vitamin D levels and the severity of erectile dysfunction. 

Decreased amounts of this vitamin could make ED worse. Those with depleted vitamin D3 could be susceptible to ED. 

Taking vitamin D might boost circulation and improve penile problems. It can also aid testosterone production, which is known to be a key aspect in improving sex life. 

Other practical vitamins are vitamin B9 (folic acid), vitamin B3, vitamin C (ascorbic acid), and L-arginine. Vitamin B9 could elevate nitric oxide production, which can help with erections. Vitamin B3 can also help patients with moderate to severe ED problems. Additionally, Vitamin C leads to better nitric oxide release and can help achieve an erection. 

Arginine supplements are particularly famous. Although it can take up to 3 months to see the benefits, L-arginine can boost sexual function. 

Based on one study in 30 patients, 17% had a significant improvement in erectile function by the end of the L-arginine trial. Although 500 mg of L-arginine 3 times a day isn’t better than a placebo, it can come in handy. Combining arginine with a Pycnogenol herbal supplement can achieve the desired result. 

For a more potent herbal treatment, people are using Panax ginseng. Also known as red ginseng, this Korean herbal remedy is very popular for ED. It is the oldest herb on the planet that can cause a hormonal impact quite like that to testosterone. 

Better testosterone and dopamine levels could facilitate erections. Plus, it has fewer side effects compared to Yohimbe. Panax ginseng can cause insomnia, upset stomach, constipation, and headaches. So, it makes for a safer alternative to Yohimbe. 


Whether you decide to use prescription medicine, a vitamin, or an herbal supplement, talk to a doctor first. Yohimbine may be more effective for ED than just a simple vitamin. But, there isn’t enough research about its long-term impact.

Some men who’ve tried the product reported moderate improvement. However, taking a vitamin or other herbal supplement may be more efficient due to its side effects. 

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  1. Corazza O, Martinotti G, Santacroce R, Chillemi E, Di Giannantonio M, Schifano F, Cellek S. Sexual enhancement products for sale online: raising awareness of the psychoactive effects of yohimbine, maca, horny goat weed, and Ginkgo biloba. Biomed Res Int. 2014. https://pubmed.ncbi.nlm.nih.gov/25025070/
  2. Susset JG, Tessier CD, Wincze J, Bansal S, Malhotra C, Schwacha MG. Effect of yohimbine hydrochloride on erectile impotence: a double-blind study. J Urol. 1989. https://pubmed.ncbi.nlm.nih.gov/2657105/
  3. Ernst E, Pittler MH. Yohimbine for erectile dysfunction: a systematic review and meta-analysis of randomized clinical trials. J Urol. 1998. https://pubmed.ncbi.nlm.nih.gov/9649257/
  4. Morales A. Yohimbine in erectile dysfunction: the facts. Int J Impot Res. 2000 Mar;12 Suppl 1:S70-74. https://pubmed.ncbi.nlm.nih.gov/10845767/
  5. Ostojic SM. Yohimbine: the effects on body composition and exercise performance in soccer players. Res Sports Med. 2006. https://pubmed.ncbi.nlm.nih.gov/17214405/
  6. Wingenfeld K, Kuffel A, Uhlmann C, Terfehr K, Schreiner J, Kuehl LK, Otte C, Löwe B, Spitzer C. Effects of noradrenergic stimulation on memory in patients with major depressive disorder. Stress. 2013.. https://pubmed.ncbi.nlm.nih.gov/22746337/
  7. Klotz T, Mathers MJ, Braun M, Bloch W, Engelmann U. Effectiveness of oral L-arginine in first-line treatment of erectile dysfunction in a controlled crossover study. Urol Int. 1999. https://pubmed.ncbi.nlm.nih.gov/10743698/

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